Maternal effect of the mutagen-sensitive mutation mus (2) 201G1 on mutagenesis in Drosophila melanogaster spermatozoid genome, induced by ethylene imine and methylmethane sulfonate
Shvartsman, P.I.; Romashkina, T.B.
Genetika 31(2): 205-208
1995
ISSN/ISBN: 0016-6758 PMID: 7721062 Document Number: 449952
The frequency of recessive sex-linked lethal mutations (RSLLM) induced in chromosome Muller-5 of mature sperms by treatment with ethyleneimine (EI) or methyl methanesulfonate (MMS) was shown to increase when male pronucleus or zygote was formed in the oocyte cytoplasm of the mutagen-sensitive line mus(2)201G1. The increase in the total number of mutations in the mutant cytoplasm was accompanied by a transformation of damages causing mosaic mutations into damage to the genome, which are recorded as complete mutations.