Determination of the lethal phase in homo- and heterozygotes for a dominant lethal cold-sensitive mutation of Drosophila melanogaster at permissive temperature
Generalova, M.V.; Miasniankina, E.N.
Genetika 22(2): 262-267
1986
ISSN/ISBN: 0016-6758 PMID: 3082716 Document Number: 277825
The lethal phase in homo- and heterozygotes for dominant cold-sensitive lethal mutation 1(2)M66DCS at permissive temperature (25 degrees C) was determined. The effective lethal phase was only revealed for homozygotes. 100% of them died during the first larval instar. In heterozygotes the mutation under study proved to be aphasic semi-lethal with 31.9% penetrance. It was localized on the left arm of chromosome 2, in position 51.2. The penetrance of some other phenotypes caused in heterozygotes at 25 degrees C was also studied.