Antifungal activity of fluconazole in vitro

Pawlik, B.; Macura, A.B.; Pawlik, B; Macura, A.B

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Antifungal activity of fluconazole in vitro

Pawlik, B.; Macura, A.B.

Medycyna Doswiadczalna i Mikrobiologia 47(1-2): 101-106

1995

ISSN/ISBN: 0025-8601

PMID: 8523965

Document Number: 452834

The susceptibility of 97 fungal strains to fluconazole was evaluated using the dilution method. Forty-three of the strains were C. albicans, fifty-three other Candida species and one S. cerevisiae. The MIC values varied from 0.1 mg/l to 100 mg/l. However, the growth of 75.2% of the strains was considerably inhibited at 0.1 mg/l. Forty-nine strains were tested using both the dilution and disk-diffusion methods. The findings were consistent. The latter method may be performed on YNB medium and is of practical value.