Nucleotide sequence of the protein E gene of the tick-borne encephalitis virus strain 595 isolated in Slovakia
Kaluzová, M.; Kaluz, S.; Kozuch, O.; Pastorek, J.; Labuda, M.
Acta Virologica 39(3): 165-169
1995
ISSN/ISBN: 0001-723X PMID: 8578999 Document Number: 448346
Tick-borne encephalitis (TBE) virus, strain 595 was isolated from Ixodes ricinus ticks in southern Slovakia. A part of the protein E gene was sequenced and compared with the prototype strain Neudorfl. Seventeen silent mutations and two amino acid changes (Ile fwdarw Val, residue 167; Asn fwdarw Thr, residue 366) were found. The nucleotide homology in the sequenced part of protein E gene of the strain 595 and the prototype strain Neudorfl is 98.6%. These findings indicate that the strain 595 is closely related to the strain Neudorfl.