How to alter the bacterial genome structure
Itaya, M.; Toda, T.; Ohshiro, Y.; Ogura, M.; Tanaka, T.
Nucleic Acids Symposium Series 34: 243-244
1995
ISSN/ISBN: 0261-3166 PMID: 8841642 Document Number: 447876
Bacterial chromosomes, mostly of circular form, have an unique primary structure that are stably maintained. We initiated a systematic study to induce changes of the structure of the Bacillus subtilis chromosome. There are two main goals: (i) to obtain general concepts for possible plasticity of the bacterial genome and (ii) to apply the proposed genome technology to bacteria.
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