Joint and systemic manifestations related to type 2 anti-mitochondrial antibodies
Dhôte, R.; Christoforov, B.; Weill, B.; Menkes, C.J.
Annales de Medecine Interne 146(8): 536-540
1995
ISSN/ISBN: 0003-410X PMID: 8734077 Document Number: 443537
The aim of the study was to assess the significance of type 2 anti-mitochondrial antibodies in patients with systemic and inflammatory rheumatic disease. Articular and systemic manifestations of 8 patients associated with type 2 anti-mitochondrial antibodies are described. All the patients had hepatic abnormalities, and 5 of them disclosed a primary biliary cirrhosis. Articular and systemic manifestations were similar to those observed in primary biliary cirrhosis. Therefore, the finding of anti-mitochondrial antibodies in patients with systemic or inflammatory rheumatic disease implies research for other systemic manifestations such as primary biliary cirrhosis.