Impact of cefetamet-pivoxil on intestinal microflora: in vivo study
Gismondo, M.R.; Drago, L.; Lombardi, A.; Fassina, C.
Journal of ChemoTherapy 6(4): 246-250
1994
ISSN/ISBN: 1120-009X PMID: 7830102 Document Number: 433061
In our study we considered the possible interference of cefetamet-pivoxil with the intestinal microflora. We used 60 germ-free mice in which an intestinal microflora similar to the human one had been implanted. They were treated with 14.3 mg/Kg/die (standard dose) and a 28.6 mg/kg/die (daily dose) of cefetamet-pivoxil by oral route. The results obtained in vivo proved that cefetamet-pivoxil at therapeutic doses does not influence the normal intestinal microflora.