A study of the in vitro and in vivo interaction of barium sulphate particles with gastro-intestinal mucus
Simmonds, R.J.; James, A.M.
Cytobios 16(62): 107-113
1976
ISSN/ISBN: 0011-4529 PMID: 16731 Document Number: 104458
The in vivo interaction of various radiopaques with mucus was investigated by a determination of the pH-mobility curves of the treated particles. Mucus covered the radiopaque particles both in vivo and in vitro. This interaction was not affected by the nature of the radiopaque or by the state of the mucous membrane. The changed state of the mucus was modified by the diet of the rat from which it was derived. The results are discussed with reference to the technique used in the administration of radiopaques.