Metabolic syndrome and intestinal microflora: what overall?
Plotnikova, E.I.; Krasnov, O.A.
Eksperimental'naia i Klinicheskaia Gastroenterologiia 12: 64-73
2014
ISSN/ISBN: 1682-8658 PMID: 26058115 Document Number: 672851
The article highlights the problem of the relationship of the intestinal microbiome person with metabolic syndrome. Changes in bacterial intestinal proportions in obesity captured the attention of scientists around the world, especially in relation to their effect on the metabolism. Increasing the proportion of Firmicutes and Actinobacteria and decrease of Bacteroidetes associated with increased levels of serum lipopolysaccharides, insulin resistance, weight gain, and other co-morbid manifestations of the metabolic syndrome. The mechanisms, underlying this interdisciplinary problems, actively studied to optimize the prevention and treatment of obesity and type 2 diabetes.