A study of intra-arterial infusion with carboplatin (CBDCA) for 2 patients with maxillary gingival cancer
Susami, E.; Uchiyama, K.; Asanami, S.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 21(7): 1063-1066
1994
ISSN/ISBN: 0385-0684 PMID: 8002622 Document Number: 431114
In 2 cases of squamous cell carcinoma of maxillary gingiva, carboplatin (CBDCA) was administered by continuous infusion for 5 days, and the clinical outcome and platinum concentrations in the peripheral blood, urine and tissue were investigated. Clinical effects were PR in one of the 2 cases and CR in the other. Platinum concentrations were as high as 3.17 and 13.90 micrograms/g in the tissue, but low in peripheral blood, not exceeding 0.61 and 0.62 micrograms/ml, respectively. These findings suggested that the present method secures the transport of the agent to a local site, with possible reduction of side effects.
Document emailed within 1 workday
Related Documents
Taguchi, T.; Kondo, M.; Tanikawa, K.; Nakamura, H.; Okawa, T.; Ogawa, N. 1993: Comparative clinical study in metastatic liver cancer between intra-arterial infusion of mitomycin C alone and intra-arterial infusion of mitomycin C combined with PJ-203 (degradable starch microspheres) Gan to Kagaku Ryoho. Cancer and ChemoTherapy 20(13): 2027-2035Yamashiro, K.; Heianna, J.; Azama, K.; Iraha, Y.; Yamashiro, T.; Kinoshita, R.; Toita, T.; Toyama, M.; Agena, S.; Maeda, H.; Suzuki, M.; Murayama, S. 2016: Maxillary Cancer with Metastasis to the Rouviere Nodes -- Complete Response to Chemoradiotherapy Using a Selective Intra-Arterial Infusion Technique Gan to Kagaku Ryoho. Cancer and ChemoTherapy 43(2): 243-246
Velotti, F.; Tubaro, A.; Stoppacciaro, A.; Pettinato, A.; Morrone, S.; Bossola, P.; Napolitano, T.; Miano, L.; Ruco, L.; Piccoli, M. 1990: Local/regional recombinant interleukin 2 (rIL-2) immunotherapy of tumors. Intra-arterial continuous infusion of rIL-2 in bladder cancer patients: a phase i study Annali Dell'istituto Superiore di Sanita 26(3-4): 411-421
Takatsuka, Y.; Fukushima, S.; Kokubu, I.; Endoh, S.; Sugitachi, A.; Kawahara, T. 1985: Intra-arterial infusion chemotherapy and transcatheter arterial chemo-embolization for patients with simultaneous bilateral breast cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 12(5): 1143-1146
Watanabe, N.; Kaneko, T.; Fujitani, S.; Umeyama, M.; Nomura, Y.; Zusho, H.; Yamada, Y.; Nanba, G.; Asahina, N.; Sugio, Y.; Okamoto, Y.; Daida, T.; Tokumaru, T. 1999: A combination of low-dose carboplatin (CBDCA) and radiation therapy in head and neck cancer patients--response and hematologenic toxicity Gan to Kagaku Ryoho. Cancer and ChemoTherapy 26(1): 101-106
Itano, S.; Hirai, K.; Kajiwara, M.; Ijuin, H.; Yoshiyama, Y.; Yoshida, T.; Sakata, K.; Ono, N.; Noguchi, H.; Sakai, T. 1994: A study of the drug distribution on intra-hepatic arterial infusion chemotherapy; how much difference between continuous infusion and rapid infusion? Gan to Kagaku Ryoho. Cancer and ChemoTherapy 21(13): 2136-2139
Watanabe, T.; Sawada, T.; Kubota, Y.; Ooya, M.; Masaki, T.; Sameshima, S.; Shinozaki, M.; Tsuno, N.; Uchiyama, M.; Sakaguchi, M. 1992: Continuous intra-arterial infusion chemotherapy in colorectal cancer patients with nonresectable metastatic liver cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 19(10 Suppl): 1515-1518
Izawa, H.; Nomura, S.; Inoue, H. 1988: Intra-arterial chemotherapy of ovarian cancer using a subcutaneously embedded reservoir--a case showing remarkable response to intermittently repeated low-dose intra-arterial infusion chemotherapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 15(1): 147-150
Fujimoto, T.; Yoshimatsu, K.; Yokomizo, H.; Umehara, A.; Watanabe, K.; Otani, T.; Matsumoto, A.; Osawa, G.; Itagaki, H.; Ogawa, K. 2007: Extra- and intra-hepatic metastasis successfully treated with alternative chemotherapy with hepatic arterial infusion and systemic intravenous infusion after responding to hepatic metastasis from colon cancer by hepatic arterial infusion--a case report Gan to Kagaku Ryoho. Cancer and ChemoTherapy 34(12): 1976-1978
Miyake, Y.; Arai, Y.; Kido, C.; Endo, T.; Sato, Y.; Ozawa, H. 1988: Changes in CT findings in patients with liver metastases of breast cancer during effective intra-arterial infusion Gan to Kagaku Ryoho. Cancer and ChemoTherapy 15(5): 1733-1737
Takatsuka, Y.; Yayoi, E.; Kobayashi, T.; Aikawa, T.; Kotsuma, Y. 1992: A prospective randomized study of intra-arterial infusion chemotherapy in the treatment of advanced breast cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 19(10 Suppl): 1617-1620
Watanabe, M.; Tsuchiya, M.; Takita, W.; Otsuka, Y.; Tamura, A.; Yamazaki, K.; Koshino, H.; Kurihara, A.; Kaneko, H.; Teramoto, T. 2006: Case report of a liver metastasis from rectal cancer achieving complete response (CR) by a combination of intra-hepatic arterial infusion of irinotecan (CPT-11) with degradable starch microspheres (DSM) and weekly high-dose intra-hepatic arterial chemotherapy with 5-FU Gan to Kagaku Ryoho. Cancer and ChemoTherapy 33(10): 1485-1488
Tada, I.; Kobayashi, M. 1985: Basic and clinical study of liver cancer using intra-arterial infusion of an emulsion of the oily contrast medium lipiodol with 5-FU Gan to Kagaku Ryoho. Cancer and ChemoTherapy 12(10): 1938-1939
Chernyĭ, V.A. 1970: The morphologic composition of peripheral blood following intra-arterial infusion of 5-fluorouracil and alkylating preparations in stomach cancer patients Voprosy Onkologii 16(4): 61-64
Inaji, H.; Noguchi, S.; Yamamoto, H.; Koyama, H.; Iwanaga, T.; Wada, A. 1989: Analysis of prognostic factors in patients with locally advanced breast cancer treated with intra-arterial infusion chemotherapy as an induction therapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 16(8 Part 2): 2910-2912
Onishi, H.; Yamaguchi, M.; Kuriyama, K.; Tsukamoto, T.; Ishigame, K.; Ichikawa, T.; Aoki, S.; Yoshikawa, T.; Araki, T.; Nambu, A.; Araki, T.; Hashi, A.; Yasumizu, T.; Hoshi, K.; Ito, H. 2000: Effect of concurrent intra-arterial infusion of platinum drugs for patients with stage III or IV uterine cervical cancer treated with radical radiation therapy Cancer Journal From Scientific American 6(1): 40-45
Kosaka, T.; Ueshige, N.; Sugaya, J.; Nakano, Y.; Akiyama, T.; Tomita, F.; Saito, H.; Kita, I.; Takashima, S. 1998: Evaluation of intra-arterial infusion chemotherapy for advanced gastric cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 25(9): 1288-1291
Iwasaki, A.; Toyama, Y.; Saitou, H.; Ohkubo, N.; Imagawa, N.; Ogawa, T.; Ohbayashi, Y.; Tanizaki, A.; Miyake, M.; Nagahata, S.; Hino, I.; Ohkawa, M. 2001: Targetting intra-arterial infusion chemotherapy with nedaplatin for oral cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 28(7): 1027-1033
An, M.; Matsumoto, Y.; Kishi, T.; Terakado, H.; Ikawa, M.; Hamada, E.; Watanabe, Y.; Nakasato, S.; Murata, M.; Takaki, S.; Miura, T.; Idezuki, Y.; Kobayashi, M. 1998: Intra-arterial infusion chemotherapy for unresectable or recurrent breast cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 25(9): 1330-1332
Sato, T.; Kawaguchi, T. 1985: Enhancement of anti-cancer effect by increased injection pressure of a single shot in intra-arterial chemotherapy--the advantage of using noradrenaline in intra-arterial chemotherapy. An experimental study Gan to Kagaku Ryoho. Cancer and ChemoTherapy 12(7): 1510-1512