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Changes in CT findings in patients with liver metastases of breast cancer during effective intra-arterial infusion

Miyake, Y.; Arai, Y.; Kido, C.; Endo, T.; Sato, Y.; Ozawa, H.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 15(5): 1733-1737

1988

ISSN/ISBN: 0385-0684
PMID: 3130809
Document Number: 318599
A study was done of the changes occurring in the CT findings of 12 cases in which liver metastases were found after radical mastectomy for breast cancer, as a result of intermittent low-dose hepatic arterial infusion chemotherapy using a reservoir, achieving PR. In four cases (33.3%) only shrinkage of the metastatic lesions was seen; in 3 others (25.0%), this was accompanied by irregularities in the margins of the liver surface; in the other 5 (41.7%), a high proportion of total, widespread compensatory deformity of the liver was observed. A tendency was noted for these changes to be more pronounced in cases in which the metastatic lesions occupied a large proportion of the liver. Hepatic degeneration appeared with a high frequency in cases where liver metastasis followed breast cancer, and it is considered that considerable care is necessary in evaluating the efficacy of treatment.

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