Top Abstract Purchase Related
Home
>
Node
>
Subnode

Safety and efficacy of an attenuated Venezuelan equine encephalomyelitis vaccine for use in Equidae

Spertzel, R.O.; Kahn, D.E.

Journal of the American Veterinary Medical Association 159(6): 731-738

1971

ISSN/ISBN: 0003-1488
PMID: 5158756
Document Number: 42931
Administration of an attenuated live-virus (TC-83) Venezuelan equine encephalomyelitis vaccine protected horses and donkeys against challenge with virulent virus. A single transient increase of body temperature was the only sign observed in vaccinated animals, and this occurred in only half of the animals responding immunologically. Viraemias below those necessary to infect susceptible mosquitoes were detected in animals from the 1st to the 6th day after vaccination. C.f. and HI antibodies appeared in the serum of all 30 horses studied under controlled experimental conditions. The sero-conversion rate for 157 Mexican horses vaccinated during a vaccination campaign was 96%.

Document emailed within 1 workday
Secure & encrypted payments

Baker, E.F.; Sasso, D.R.; Maness, K.; Prichard, W.D.; Parker, R.L. 1978: Venezuelan equine encephalomyelitis vaccine (strain TC-83): a field study American Journal of Veterinary Research 39(10): 1627-1631
Bondarenko, E.I.; Protopopova, E.V.; Konovalova, S.N.; Surovtsev, I.V.; Mal'tsev, V.P.; Loktev, V.B. 2004: Laminin-binding protein as a cellular receptor for the equine Venezuelan encephalomyelitis virus: Report 2. Inhibition of replication of equine Venezuelan encephalomyelitis virus by blocking laminin-binding protein on the surface of Vero cells Molekuliarnaia Genetika Mikrobiologiia i Virusologiia 2004(1): 36-40
Walton, T.E.; Johnson, K.M. 1972: Epizootiology of Venezuelan equine encephalomyelitis in the Americas Journal of the American Veterinary Medical Association 161(11): 1509-1515
Omohundro, R.E. 1972: Venezuelan equine encephalomyelitis emergency operation Journal of the American Veterinary Medical Association 161(11): 1516-1518
Zaĭtseva, O.V.; Posevaia, T.A.; Ershov, F.I.; Kosiakov, P.N.; Sokolova, T.M. 1975: Neutralization of Venezuelan equine encephalomyelitis virus by anticellular serums Voprosy Virusologii 1: 78-82
Roberts, E.D.; Sanmartin, C.; Payán, J.; Mackenzie, R.B. 1970: Neuropathologic changes in 15 horses with naturally occurring Venezuelan equine encephalomyelitis American Journal of Veterinary Research 31(7): 1223-1229
Sokolova, T.M.; Tazulakhova, I.B.; Grigorian, S.S.; Ershov, F.I. 1974: Reproduction of the Venezuelan equine encephalomyelitis virus under conditions of low ionic strength Voprosy Virusologii 5: 586
Kharitonenkov, I.G.; Gaĭdamovich, S.I.; Pomelova, V.G.; Sokolova, M.V.; Lavrova, N.A.; Leonov, S.V.; Zlobin, V.N. 1990: A rapid isolation of Venezuelan equine encephalomyelitis virus using the lanthanide immunofluorescence assay Voprosy Virusologii 35(1): 77-79
Tsilinskiĭ, I.I.; Gushchin, B.V.; Klimenko, S.M.; L'vov, D.K. 1971: Relation between the biological properties of Venezuelan equine encephalomyelitis virus and dimensions of the virions Voprosy Virusologii 16(5): 573-576
Dickerman, R.W.; Bonacorsa, C.M. 1975: Venezuelan equine encephalomyelitis viral infection of newly hatched chickens and embryonating eggs American Journal of Veterinary Research 36(8): 1231-1233
Bakanidze, L.G.; Leont'eva, N.A. 1988: Effect of remantadine on the morphogenesis of the Venezuelan equine encephalomyelitis virus in a Vero cell culture Voprosy Virusologii 33(1): 81-86
Gaĭdamovich, S.I.; Tsilinskiĭ, I.I.; L'vova, A.I.; Khutoretskaia, N.V. 1971: Characteristics of multiplication of different clones of Venezuelan equine encephalomyelitis virus in Aëdes aegypti mosquitos Meditsinskaia Parazitologiia i Parazitarnye Bolezni 40(3): 267-271
Derkach, I.S.; Uryvaev, L.V.; Zhdanov, V.M. 1972: Study of protein components of the Venezuelan equine encephalomyelitis virus by electrophoresis and isoelectric focusing Voprosy Virusologii 17(2): 211-214
Karpova, E.F.; Tsilinskiĭ, I.I.; Gushchin, B.V.; Gushchina, E.A.; Klimenko, S.M. 1984: Biological and genetic properties of a polyploid-forming mutant of the Venezuelan equine encephalomyelitis virus Voprosy Virusologii 29(2): 195-200
Levitt, N.H.; Miller, H.V.; Pedersen, C.E.; Eddy, G.A. 1975: A microprecipitation test for rapid detection and identification of Venezuelan, eastern and western equine encephalomyelitis viruses American Journal of Tropical Medicine and Hygiene 24(1): 127-130
Il'ichev, A.A.; Melamed, N.V.; Razumov, I.A.; Maksiutov, A.Z.; Pereboev, A.V.; Zakabunin, A.I.; Loktev, V.B. 1996: Expression of fragments of Venezuelan equine encephalomyelitis virus E2 protein in a system based on phage T7 RNA polymerase Molekuliarnaia Biologiia 30(1): 76-83
Jochim, M.M.; Barber, T.L.; Luedke, A.J. 1973: Venezuelan equine encephalomyelitis: antibody response in vaccinated horses and resistance to infection with virulent virus Journal of the American Veterinary Medical Association 162(4): 280-283
Bigler, W.J.; Ventura, A.K.; Lewis, A.L.; Wellings, F.M.; Ehrenkranz, N.J. 1974: Venezuelan equine encephalomyelitis in Florida: endemic virus circulation in native rodent populations of Everglades hammocks American Journal of Tropical Medicine and Hygiene 23(3): 513-521
Linthicum, K.J.; Gordon, S.W.; Monath, T.P. 1992: Comparative infections of epizootic and enzootic strains of Venezuelan equine encephalomyelitis virus in Amblyomma cajennense (Acari: Ixodidae) Journal of medical entomology 29(5): 827-831
Zhirnov, O.P.; Bukrinskaia, A.G.; Mel'nikova, E.E.; Gaĭdamovich, S.I.; Novokhatskiĭ, A.S. 1985: Identification of monoclonal antibodies against protein E1 of venezuelan equine encephalomyelitis virus blocking the hemagglutinating but not the infective activity of virions Molekuliarnaia Genetika Mikrobiologiia i Virusologiia 8: 31-35