Venezuelan equine encephalomyelitis: antibody response in vaccinated horses and resistance to infection with virulent virus

Jochim, M.M.; Barber, T.L.; Luedke, A.J.

Journal of the American Veterinary Medical Association 162(4): 280-283

1973


ISSN/ISBN: 0003-1488
PMID: 4686185
Document Number: 61107
Three groups of ten horses each were vaccinated with three different concentrations of attenuated VEE virus (strain TC-84). Their susceptibility to virulent VEE virus was tested 14 to 28 days later. Horse with plaque-neutralizing antibody titres of 1:40 or greater resisted challenge infection. All ten horses given the recommended minimum dose of vaccine developed titres of 1:80 or greater. Inoculation of attenuated virus was followed by a mild systemic reaction.

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