Venezuelan equine encephalomyelitis vaccine (strain TC-83) : a field study
Baker, E.F.; Sasso, D.R.; Maness, K.; Prichard, W.D.; Parker, R.L.
American Journal of Veterinary Research 39(10): 1627-1631
1978
ISSN/ISBN: 0002-9645 PMID: 717877 Document Number: 138043
In 1971, more than 370 horses in south Texas were studied for clinical, virological, and neutralizing antibody responses to vaccination with Venezuelan equine encephalomyelitis (VEE) strain TC-83. This study confirms the findings that the vaccine used in the 1971 outbreak in the lower Rio Grande Valley of Texas was safe and efficacious. Vaccinal virus viraemia titres were generally below the postulated infection threshold of epizootic vectors. In general, reactions to the vaccine were minimal and transient, with no observed abortions or deaths attributable to use of the vaccine. Eleven months after vaccination, VEE antibody titres were present in most horses that had VEE antibodies within 30 days after vaccination. Presence of western equine encephalomyelitis antibody titres of 1:50 or above at time of VEE vaccination appears to modify or to interfere with VEE antibody production.