Uptake1, uptake2 and the release of [3H]-noradrenaline in uterine artery of pigs during the oestrous cycle
Dynarowicz, I.; Trapkowski, T.; Pirus, T.
Archivum Veterinarium Polonicum 33(3-4): 259-267
1993
ISSN/ISBN: 1230-5359 PMID: 10187991 Document Number: 416238
Neuronal uptake (uptake1), extraneuronal uptake (uptake2) and the spontaneous release of superscript 3H-noradrenaline (NA) in uterine artery in pigs on days 0, 1-2, 13-14 and 16-18 of the oestrous cycle were studied. It was found that uptake1 was the lowest on the day of ovulation (day 0) and then it increased by 37.4% and by 93.7% on days 1-2 and 13-14, respectively. On days 16-18 of the oestrus cycle uptake1 was significantly higher (9.3%) compared to day 0. Uptake2 was the lowest on day 0 and it then increased to 180.1% on days 1-2. Thereafter it decreased to 140.3% on days 13-14 and 113.8% on days 16-18 of the oestrous cycle. Release of neuronal radioactivity was the lowest on day 0 and then it increased by 40.0-44.2%, 46.8-49.5% and 26.1-28.1% on days 1-2, 13-14 and 16-18 of the oestrous cycle respectively. The release of the extraneuronal radioactivity was the highest on day 0 (defined as 100%) and similarly high (88.6-91.8%) on days 13-14 but markedly lower (28.3-36.0%) on days 1-2 and 16-18 (43.9-50.1%). The relationship between U1, U2, extra- and neuronal release of noradrenaline and concentrations of oestrogens and progesterone during oestrous cycle are discussed.