Spectroscopic studies of the interaction of synthetic RNAs with quinacrine and its analogs
Nakamura, S.; Yoshimatsu, S.; Murakami, K.; Kubota, Y.
Nucleic Acids Symposium Series 27: 75-76
1992
ISSN/ISBN: 0261-3166 PMID: 1283918 Document Number: 398807
The interaction of synthetic RNAs with quinacrine (QAC) and its analogs has been studied by absorption, fluorescence and circular dichroism (CD) measurements. The results indicate that the 2-methoxy group of the acridine ring plays an important role in the appearance of the new absorption band upon binding of QAC to poly-(rA).poly(rU).
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