Comparative efficacy of levo-praziquantel and praziquantel in treatment of schistosomiasis japonica at a single dose
Wu, M.H.; Wei, C.C.; Xu, Z.Y.; Yuan, H.C.; Lian, W.N.; Yang, Q.J.; Chen, M.; Wang, C.Z.; Zhang, Z.J.; Liu, Z.D.
Chinese Medical Journal 104(9): 732-735
1991
ISSN/ISBN: 0366-6999 PMID: 1935353 Document Number: 386778
The result of a randomized double blind comparison of therapeutic efficacy of single doses of levo-praziquantel (L-PZQ) and praziquantel (PZQ) in the treatment of 139 matched pairs of proved cases of schistosomiasis japonica was reported, 268 were chronic early cases and 10 were late cases. The dosage of L-PQZ was 20 mg/kg, and that of PZQ was 40 mg/kg. Four and 6 months after treatment the stool-ova negative conversion rates were 94.8% and 96.3% for the L-PZQ group, and 97.1% and 94.0% for the PZQ group respectively (P greater than 0.05).