Oligomeric forms of recombinant interleukin-2
Meriin, A.B.; Ivaniushina, V.A.; Kiselev, O.I.
Biokhimiia 56(10): 1832-1839
1991
ISSN/ISBN: 0320-9725 PMID: 1777522 Document Number: 380157
Human recombinant interleukin 2 produced by Escherichia coli gives rise to oligomeric forms that are stable to complete denaturation. The appearance of these forms is preceded by the formation of oligomers sensitive to reduction. These processes depend on the cell status and seem to be associated with aggregation of the reaction product.
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