Studies on the mutagenicity of vesnarinone
Hu, H.; Xing, Y.; Tao, D.; Zheng, X.; Yang, Z.
Hua Xi Yi Ke Da Xue Xue Bao 22(2): 140-143
1991
ISSN/ISBN: 0257-7712 PMID: 1786949 Document Number: 368348
The mutagenicity of domestic Vesnarinone (OPC-8212) was studied by Ames test, micronucleus test of NIH mouse bone marrow and chromosome aberration assay in CHL cells. Negative results were obtained, which suggested that OPC-8212 did not induce prokaryotic cell gene mutation or chromosome damage both in vitro and in vivo.
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