Peripheral nerve involvement in ataxia telangiectasia: histological and ultrastructural studies of peroneal nerve biopsy in two cases
Malandrini, A.; Guazzi, G.C.; Alessandrini, C.; Federico, A.
Clinical Neuropathology 9(3): 109-114
1990
ISSN/ISBN: 0722-5091 PMID: 2163784 Document Number: 365312
The authors report a histological and electron-microscopic study of the peripheral nerve in two cases of ataxia-telangiectasia showing fiber loss, storage material in Schwann cells and nuclear changes. Nuclear changes are the most typical finding and are correlated with the primary metabolic disorder of DNA repair.
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