Antitumor activity of methyl-4 H-1,2,4-benzothiadiazin-3-yl-carbamodithioate-S,S,-dioxide
Tait, A.; Di Bella, M.
Bollettino Chimico Farmaceutico 129(9): 273-275
1990
ISSN/ISBN: 0006-6648 PMID: 2098054 Document Number: 362512
The antitumor activity of the methyl-6-chloro-4H-1,2,4-benzothiadiazin-3-yl-S-carbamothioate+ ++-S,S,-dioxide (1) and the methyl-4H-1,2,4-benzothiadiazin-3-yl-carbamodithioate-S,S-di oxide (2), has been evaluated. Compound 2 passed activity criteria for leukemia P388 and was also moderately active against transplanted mouse tumor L1210 leukemia and M5076 sarcoma.
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