Isolation of Staphylococcus hyicus subsp. hyicus from pigs affected with exudative epidermitis and experimental infection of piglets with isolates
Sato, H.; Tanabe, T.; Nakanowatari, M.; Oyama, J.; Yamazaki, N.; Yoshikawa, H.; Yoshikawa, T.; Koyama, H.; Saito, H.
Kitasato Archives of Experimental Medicine 63(2-3): 119-130
1990
ISSN/ISBN: 0023-1924 PMID: 2096257 Document Number: 360849
Five strains of S. hyicus subsp. hyicus were isolated: 3 strains (P-1, P-2 and P-3) from the crust on the body surface of 6-month-old pigs on a farm in Aomori prefecture, and 2 (P-5 and P-6) from both the crust on the body surface and the joint of a 1-month-old piglet with exudative epidermitis (EE) on another farm. The characterization of the isolates and the experimental infection of the piglets with strain P-1 were carried out. Subcutaneous inoculation with the bacterial suspension (1010 CFU) produced EE in all 9 piglets. Eight of them had exudation and exfoliation within 24 h of infection. Histopathologically, disappearance of stratum corneum and necrosis with vacuolar degeneration of prickle cells were pronounced in the epidermis. Infiltration of neutrophils and lymphocytes were observed in the epidermis. The results indicate that S. hyicus is responsible for incrustation of the body surface of weanling pigs and exudative epidermitis in young piglets.