Method of optimization of the solvent system for thin layer chromatography
Ban, Y.D.; Sun, Y.Q.; Zhang, J.B.
Yao Xue Xue Bao 24(11): 841-846
1989
ISSN/ISBN: 0513-4870 PMID: 2618682 Document Number: 340661
In this article, we analyzed 81 usual solvents with Fuzzy group analytical method by a computer at first and selected 20 better solvents for TLC. Then the solvent system for TLC was optimized by means of uniform design test and optimization method.sbd.simplex method. We also worked out a modified chromatographic optimization function. This systematized method has been shown to be effective and practical in our experiments. It is not only fit for TLC, but also for paper chromatography and liquid chromatography. So far, no similar report has been found in the literature.