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Effect of thymalin on the immunological indices and morphofunctional structure of the uterus in guinea pigs with endometrial hyperplasia

Zaporozhan, V.N.; Khait, O.V.; Li, L.N.

Biulleten' Eksperimental'noi Biologii i Meditsiny 107(2): 251-253

1989

ISSN/ISBN: 0365-9615
PMID: 2784333
Document Number: 339597
The efficiency of usage of the preparations of thymalin in hyperplasia of endometrium has been studied in the experiment on 125 female guinea pigs. Indicated pathology was caused by the introduction of oil solution of synestrol during 19 weeks. It is determined that marked hyperplasia of endometrium is developing as a result of prolonged introduction of synestrol in experimental animals and the decrease of the amount of T- and B-lymphocytes takes place. The use of thymalin results in normalization of indexes of immune system and in partial normalization of morphologic structure of endometrium.

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