The antioxidative properties of thiazolidine derivatives

Włodek, L.; Czubak, J.

Polish Journal of Pharmacology and Pharmacy 41(4): 369-375

1989


ISSN/ISBN: 0301-0244
PMID: 2634830
Document Number: 335690
Antioxidative properties of thiazolidine compounds, adducts of L-cysteine with formaldehyde (thiazolidine-4-carboxylic acid), with pyruvate (2-methyl-thiazolidine-2,4-dicarboxylic acid), and glucose (2-/D-gluco-1',2',3',4',5'-penthahydroxypentyl/- thiazolidine-4-carboxylic acid) were studied. The investigated compounds, as well as L-cysteine and DL-penicillamine inhibited in vitro lipid peroxidation induced by NADPH, ethanol, and hydrogen peroxide in the suspension of rat liver microsomes.

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