Inhibitory effect of sulphur-containing purine nucleoside analogues on replication of RNA viruses: selective antiviral activity against influenza viruses

Yamamoto, K.; Hasobe, M.; Saneyoshi, M.

Acta Virologica 32(5): 386-392

1988


ISSN/ISBN: 0001-723X
PMID: 2904732
Document Number: 324927
Four sulphur-containing purine nucleoside analogues: 6MP, 6-thioinosine, 6-methylthioinosine and 6-ethylthioinosine, were examined for antiviral activity against some RNA viruses. All compounds extensively inhibited the replication of influenza viruses but had no inhibitory effect on other RNA viruses: Sendai, RS, vesicular stomatitis and western equine encephalitis viruses.

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