The effect of sorbose on NAD (P) ase production by Aspergillus nidulans
da-Silva, R.; Jorge, J.A.
Brazilian Journal of Medical and Biological Research 21(4): 735-745
1988
ISSN/ISBN: 0100-879X PMID: 2853639 Document Number: 312244
1. NAD(P)ase activity was stimulated when 1% sorbose was present in the culture medium of A. nidulans, and this effect was partially reversed by 1% glucose. 2. The level of extracellular NAD(P)ase was more affected by sorbose in the culture medium than the intracellular enzyme and no morphological changes were obtained. 3. The sorbose effect on NAD(P)ase activity appears to be specific since two other exoenzymes tested (beta-glucosidase and alkaline protease) show normal secretion patterns. 4. These findings suggest that the sorbose effect on NAD(P)ase production may be the consequence of metabolic disorders not necessarily linked with the morphological changes induced by the ketohexose.