Cysteine biosynthesis in Aspergillus nidulans
Steień, P.P.; Pieniqzek, N.J.; Bal, J.; Morzycka, E.
Acta Microbiologica Polonica. Series A Microbiologia Generalis 7(4): 201-210
1975
ISSN/ISBN: 0567-7815 PMID: 1108603 Document Number: 92274
The existence of two postulated pathways of anabolic cysteine biosynthesis in Aspergillus midulans was investigated. No activities of the postulated pathway involving S-sulfocysteine as intermediate have been detected. Investigations on cyteine and methionine requiring mutants revealed independent regulation of O-acetylserine sulfhydrylase by endogeneous cysteine and methionine pools. The reaction catalysed by O-acetylserine sulfhydrylase is postulated as the only anabolic pathway of cysteine biosynthesis in A. nidulans.