Fatty acids of the omega-3 line in the erythrocytes of Chukchi with myocardial hypertrophy
Gerasimova, E.N.; Ozerova, I.N.; Shal'nova, S.A.; Levachev, M.M.; Kulakova, S.N.
Terapevticheskii Arkhiv 60(6): 98-103
1988
ISSN/ISBN: 0040-3660 PMID: 2974646 Document Number: 311558
A study was made of the fatty acid composition of erythrocytes in the Chukchi aged 30 to 59 with myocardial hypertrophy and in controls. In erythrocytes of the Chukchi the percentage of polyunsaturated fatty acids of omega-3 series including eicosapentaenoic acid was increased (C 20:5), and the percentage of linoleic acid and arachidonic acid was decreased (C 18:2 and C 20:4, respectively) as compared to similar indices of erythrocytes in Muscovites. Myocardial hypertrophy was diagnosed in the Chukchi in whom the percentage C 20:5 in erythrocytes was higher and exceeded that in PL. It was assumed that changes in the fatty acid composition of cell membranes played certain part in disorder of their function and the development of myocardial hypertrophy in the Chukchi.