The biotransformation of fenetylline
Rücker, G.; Neugebauer, M.; Heiden, P.G.
Arzneimittel-Forschung 38(4): 497-501
1988
ISSN/ISBN: 0004-4172 PMID: 3401264 Document Number: 309284
After oral administration of 3,7-dihydro-1,3-dimethyl-7-2 [(1-methyl-2-phenylethyl)-amino-ethyl]-1H-purine-2,6-dione (fenetylline, Captagon), 7 new metabolites could be detected in urine besides 4 known substances. The metabolites were identified by gas chromatography (GC) and by comparison of the mass spectra (MS) of metabolites with those of authentic reference compounds using a combined GC/MS method.