Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effect of aminazine and triftazin on the synaptosome membranes of the rat cerebral cortex

Avdulov, N.A.; Eremenko, A.V.; Val'dman, A.V.

Biulleten' Eksperimental'noi Biologii i Meditsiny 105(2): 173-175

1988

ISSN/ISBN: 0365-9615
PMID: 3349147
Document Number: 308944
Fluorescent probes 1,6-diphenyl-1,3,5-hexatriene (DPH) and pyrene were employed in studying the effect of aminazine and triftazin versus that of imipramine on microviscosity of rat brain cortex synaptosomal membranes. Unlike imipramine, the neuroleptics decrease microviscosity of membrane's lipid bilayer. All drugs decrease fluorescence of endogenous tryptophan, but fail to change fluorescence of L-tryptophan in the solution. It is concluded that neuroleptics induce conformational perturbations in membrane-bound proteins modifying microviscosity of lipid bilayer whereas imipramine changes the surface electric charge of lipid bilayer of synaptosomal membranes.

Document emailed within 1 workday
Secure & encrypted payments

Kryzhanovskiĭ, G.N.; Sandalov, I.G.; Rodina, V.I.; Rozhanets, V.V.; Glebov, R.N. 1977: Effect of tetanus toxin and colchicine on synaptic membranes of rat cerebral cortex Biulleten' Eksperimental'noi Biologii i Meditsiny 83(2): 139-142
Makogonenko, E.M.; Grinenko, T.V.; Kudinov, S.A. 1974: Effect of SH-reagents on the Mg2+-dependent Ca2+-activated ATPase activity of synaptosome plasma membranes Ukrains'kyi Biokhimichnyi Zhurnal 46(5): 553-560
Gaevyĭ, M.D.; Trofimenko, S.P. 1975: Effect of aminazine on cerebral circulation Biulleten' Eksperimental'noi Biologii i Meditsiny 80(10): 72-74
Castejon, O.J. 2004: Ultrastructural pathology of neuronal membranes in the oedematous human cerebral cortex Journal of Submicroscopic Cytology and Pathology 36(2): 167-179
Frontczak-Baniewicz, M. 2001: Focal ischemia in the cerebral cortex has an effect on the neurohypophysis. I. Ultrastructural changes in capillary vessels of the neurohypophysis after focal ischemia of the cerebral cortex Neuro Endocrinology Letters 22(2): 81-86
Miloslavskiĭ, I.M.; Oslopov, V.N. 1975: Changes in the glucocorticoid function of the adrenal cortex in patients with myocardial infarct treated with trioxazine and aminazine Kardiologiia 15(8): 77-83
Cook, D.A.; Bielkiewicz, B. 1985: The effect of phenoxybenzamine on histamine H1-receptor binding sites in dog frontal cortex membranes Proceedings of the Western Pharmacology Society 28: 213-215
Popova, E.N. 1979: Effect of alcohol on cerebral cortex neurons Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 79(12): 1674-1678
Shandra, A.A.; Godlevskiĭ, L.S. 1981: Effect of cerebellectomy on strychnine foci in the cerebral cortex Biulleten' Eksperimental'noi Biologii i Meditsiny 92(7): 14-16
Pavlovskaia, N.I.; Vorob'eva, T.V.; Zelenin, V.A. 1986: Effect of nootropil on the ultrastructure of the cerebral cortex of the aged rat Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 86(7): 1012-1016
Gaĭdamkin, N.A.; Davydov, B.I.; Zuev, V.G.; Tikhonchuk, V.S. 1988: Ultrastructure of the cerebral cortex in the rat after the effect of electromagnetic impulse Arkhiv Anatomii Gistologii i Embriologii 95(7): 14-18
Pavlinova, L.I.; Gerasimova, I.A.; Bagaeva, T.R.; Emel'ianov, N.A. 1991: Effect of hydrocortisone on phosphoinositide metabolism in rat cerebral cortex slices Ukrainskii Biokhimicheskii Zhurnal 63(1): 85-87
Shaliapina, V.G. 1974: Effect of corticosteroids on noradrenaline absorption by rat cerebral cortex slices Problemy Endokrinologii 20(4): 78-81
Iasnetsov, V.V.; Pravdivtsev, V.A.; Krylova, I.N.; Kozlov, S.B.; Provornova, N.A.; Ivanov, I.V.; Iasnetsov, V.V. 2001: Effect of nootropic agents on impulse activity of cerebral cortex neurons Eksperimental'naia i Klinicheskaia Farmakologiia 64(6): 3-6
Soulairac, M.L.; Soulairac, A. 1972: Effect of neurostimulating substances on sex behavior of the male rat after cerebral cortex lesions Journal de Physiologie 65(Suppl 3): 504a
Hochwald, G.M.; Altszuler, N.; Gandhi, M. 1978: Effect of phentolamine and adrenalectomy on hyperglycemic response following puncture of the cerebral cortex Transactions of the American Neurological Association 103: 250-252
Poli, A.; Contestabile, A.; Migani, P.; Rondelli, C.; Rossi, L.; Virgili, M.; Barnabei, O. 1984: Effect of kainic acid on the release of exogenous neurotransmitters from synaptosome preparations Bollettino della Societa Italiana di Biologia Sperimentale 60(Suppl 4): 93-98
Shandra, A.A.; Godlevskiĭ, L.S. 1983: Effect of electric stimulation of the fastigial nucleus on epileptic activity in the cerebral cortex Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 1983(6): 29-34
Gabrielian, E.S.; Matevosian, R.S. 1984: Effect of calcium blockers on the morphofunctional state of the capillary system of the cerebral cortex Biulleten' Eksperimental'noi Biologii i Meditsiny 98(9): 310-312
Linares, H.; Proverbio, T.; Rawlins, F.; Proverbio, F. 1980: Effect of the partial substitution of membrane cholesterol by 7-dehydrocholesterol on the movement of Na, K and Cl in slices of the rat cerebral cortex Acta Cientifica Venezolana 31(6): 566-571