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Effect of nootropil on the ultrastructure of the cerebral cortex of the aged rat

Pavlovskaia, N.I.; Vorob'eva, T.V.; Zelenin, V.A.

Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 86(7): 1012-1016

1986

ISSN/ISBN: 0044-4588
PMID: 3765983
Document Number: 273717
The brain cortex was studied in 7 Wistar rats aged 25-35 months. Rats receiving nootropil (piracetam) showed intracellular regeneration (enrichment of neuronal nuclei for chromatin, increased degree of plication of nuclear membrane, nucleolar hypertrophy, increase in the number of cellular organellae which created a picture of perinuclear hyperchromatosis). Another important effect of nootropil was dramatic reduction of hydropsy of the neural tissue. Nootropil use was also associated with the development and strengthening of the compensatory/adaptive reaction expressed on the morphological level by the development of comprehensive structural contacts of astrocytes, oligodendrocytes and capillaries with different parts and each other. The use of nootropil made it possible to ascertain the reversible pattern of some morphological changes related to physiological aging.

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Gaĭdamkin, N.A.; Davydov, B.I.; Zuev, V.G.; Tikhonchuk, V.S. 1988: Ultrastructure of the cerebral cortex in the rat after the effect of electromagnetic impulse Arkhiv Anatomii Gistologii i Embriologii 95(7): 14-18
Mikeladze, A.L.; Kutateladze, I.I. 1972: Ultrastructure of the cerebral cortex during strychnine application Biulleten' Eksperimental'noi Biologii i Meditsiny 73(10): 113-116
Carrascal, E.; Campora, R.G.; Bullón, M.; Fernández, J.; Galera, S.H. 1977: Ultrastructure of the dark neurons of the cerebral cortex Archivos de Neurobiologia 40(3): 165-176
Reyners, H.; De Reyners, E.G.; Maisin, J.R. 1979: Late effects of irradiation on the cerebral cortex ultrastructure of the rat Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 173(3): 669-676
Popova, E.N. 2001: Ultrastructure of the cerebral cortex neurons in atherosclerotic dementia Morfologiia 119(2): 11-14
Selwood, L. 1971: Ultrastructure of neuroglia in the cerebral cortex of the bandicoot Perameles nasata (Marsupialia) Journal of Anatomy 110(Part 3): 498
Spacek, J. 2005: Contribution of serial electron microscopy to study of ultrastructure of cerebral cortex Casopis Lekaru Ceskych 144(Suppl 3): 6-8
Malunova, L.B.; Vorob'ev, V.S.; Samoĭlov, M.O. 1983: Ultrastructure of the cerebral cortex of the cat in the early recovery period after short-term anoxia Tsitologiia 25(11): 1259-1263
Frontczak-Baniewicz, M. 2001: Focal ischemia in the cerebral cortex has an effect on the neurohypophysis. I. Ultrastructural changes in capillary vessels of the neurohypophysis after focal ischemia of the cerebral cortex Neuro Endocrinology Letters 22(2): 81-86
Popova, E.N. 1979: Effect of alcohol on cerebral cortex neurons Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 79(12): 1674-1678
Shandra, A.A.; Godlevskiĭ, L.S. 1981: Effect of cerebellectomy on strychnine foci in the cerebral cortex Biulleten' Eksperimental'noi Biologii i Meditsiny 92(7): 14-16
Avdulov, N.A.; Eremenko, A.V.; Val'dman, A.V. 1988: Effect of aminazine and triftazin on the synaptosome membranes of the rat cerebral cortex Biulleten' Eksperimental'noi Biologii i Meditsiny 105(2): 173-175
Shaliapina, V.G. 1974: Effect of corticosteroids on noradrenaline absorption by rat cerebral cortex slices Problemy Endokrinologii 20(4): 78-81
Pavlinova, L.I.; Gerasimova, I.A.; Bagaeva, T.R.; Emel'ianov, N.A. 1991: Effect of hydrocortisone on phosphoinositide metabolism in rat cerebral cortex slices Ukrainskii Biokhimicheskii Zhurnal 63(1): 85-87
Wu, W.; Kuang, P.; Zhu, K. 1992: The effect of radix Salviae miltiorrhizae on the changes of ultrastructure in rat brain after cerebral ischemia Journal of Traditional Chinese Medicine 12(3): 183-186
Artiukhina, N.I. 1975: Effect of visual deafferentiation on the ultrastructure of synapses of the rat visual cortex Arkhiv Anatomii Gistologii i Embriologii 68(4): 12-18
Hochwald, G.M.; Altszuler, N.; Gandhi, M. 1978: Effect of phentolamine and adrenalectomy on hyperglycemic response following puncture of the cerebral cortex Transactions of the American Neurological Association 103: 250-252
Soulairac, M.L.; Soulairac, A. 1972: Effect of neurostimulating substances on sex behavior of the male rat after cerebral cortex lesions Journal de Physiologie 65(Suppl 3): 504a
Kryzhanovskiĭ, G.N.; Sandalov, I.G.; Rodina, V.I.; Rozhanets, V.V.; Glebov, R.N. 1977: Effect of tetanus toxin and colchicine on synaptic membranes of rat cerebral cortex Biulleten' Eksperimental'noi Biologii i Meditsiny 83(2): 139-142
Iasnetsov, V.V.; Pravdivtsev, V.A.; Krylova, I.N.; Kozlov, S.B.; Provornova, N.A.; Ivanov, I.V.; Iasnetsov, V.V. 2001: Effect of nootropic agents on impulse activity of cerebral cortex neurons Eksperimental'naia i Klinicheskaia Farmakologiia 64(6): 3-6