Use of sheep erythrocytes and plasma for the determination of neuroparalytic substances in vitro

Nistiarová, A.; Nistiar, F.; Bajgar, J.

Veterinarni Medicina 32(6): 365-369

1987


ISSN/ISBN: 0375-8427
PMID: 3113033
Document Number: 301245
A simple method of the determination of nerve-paralytic substances is presented, based on the use of ram erythrocytes and plasma with the determination of cholinesterase inhibition. Dichlorvos administered at the rate of 94.64 ng per litre induced 50% inhibition of acetylcholinesterase in the erythrocytes; administration of dichlorvos at the rate of 243.82 ng per litre caused a 50% inhibition of butyrylcholinesterase in the plasma.

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