Protective properties of microcrystalline cellulose in experimental diabetes mellitus in rats
Vaĭnshteĭn, S.G.; Zhulkevich, I.V.; Petropavlovskiĭ, G.A.; Kotel'nikova, N.E.
Biulleten' Eksperimental'noi Biologii i Meditsiny 103(2): 167-168
1987
ISSN/ISBN: 0365-9615 PMID: 3028529 Document Number: 297945
The experiments on 45 inbred male and female rats with alloxan diabetes have shown that microcrystalline cellulose at a dose of 3 g/day received per os beginning from day 15 to day 42 after alloxan administration stabilizes the animals' body mass, reduces the level of glycemia and glycosylated hemoglobin. A parallel reduction of triglyceride and total cholesterol levels and increase in plasma phospholipid content, compared to the control, are observed, as well as a considerable hypocoagulation shift in the blood aggregation system.