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The sensitivity to trypanocidal drugs of Trypanosoma vivax isolated in Kenya and Somalia

Schönefeld, A.; Röttcher, D.; Moloo, S.K.

Tropical Medicine and Parasitology Official Organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit 38(3): 177-180

1987

ISSN/ISBN: 0177-2392
PMID: 3432953
Document Number: 297769
The drug sensitivity of 7 T. vivax isolates from Kenya and Somalia was examined. With the exception of diminazene aceturate all commercially available trypanocidal drugs failed to effect a cure. The results suggest the existence of multiple drug resistance of T. vivax strains, geographically widely distributed along the East African Coast. The isolates were resistant to the recommended dose rates of isometamidium, homidium and quinapyramine. Isometamidium showed no prophylactic properties when tested against one of the isolates. All were sensitive to diminazene aceturate.

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