Changes in brain energy metabolism in experimental cerebral hemorrhage
Maslov, L.N.
Voprosy Meditsinskoi Khimii 33(1): 59-62
1987
ISSN/ISBN: 0042-8809 PMID: 3577058 Document Number: 296236
Intracerebral hemorrhage impaired the functional activity of rat brain mitochondria. After experimental insult the rate of succinate and alpha-ketoglutarate oxidation was decreased at the states 3 and 4 in brain mitochondria as well as in presence of 2,4-dinitrophenol. The rate of phosphorylation was also decreased in oxidation of both NAD- and FAD-dependent substrates.
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