Activation of lipid peroxidation in the brain in cerebral hemorrhage
Plotnikov, M.B.; Lobanov, A.A.; Ivanov, V.V.
Biulleten' Eksperimental'noi Biologii i Meditsiny 105(6): 677-678
1988
ISSN/ISBN: 0365-9615 PMID: 3390586 Document Number: 309484
The effect of intracerebral hemorrhage (injection of 0.15 ml of autogenic blood during 2 min in capsula interna) on lipid peroxidation in brain tissue was studied in rat experiments. Intracerebral hemorrhage resulted in a progressive increase of conjugated diene and malonic dialdehyde concentrations, and a decrease in the levels of cerebral lipids antiradical activity. This effect appeared by the 3-rd hour and was significantly manifest 24 hours after the blood injection into the brain.