A case of breast cancer with pleural metastasis responding to administration of intrapleural adriamycin and systemic chemotherapy with FEMP
Ogasahara, K.; Takeda, R.; Nishizawa, F.; Yoshimura, T.; Denno, R.; Adachi, Y.; Takahashi, J.; Kohno, Y.; Bada, K.; Ohbayashi, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 14(11): 3140-3142
1987
ISSN/ISBN: 0385-0684 PMID: 3118815 Document Number: 296057
A 51-year-old woman with breast cancer metastatic to the pleura was treated with intrapleural instillation of adriamycin after thoracentesis, and systemic administration of FEMP, with complete response for more than 11 months. She underwent radical mastectomy and bilateral oophorectomy for advanced breast cancer, and 18 months later presented radiological evidence of pleural fluid contralateral to the affected breast. Initially, thoracentesis for symptomatic relief was done with a positive cytology in the pleural effusion. Intrapleural instillation of adriamycin was followed by partial resolution, and administration of FEMP achieved complete disappearance of both pleural metastasis and pleural effusion.