A case of gastric cancer with multiple liver metastasis responding to combined chemotherapy with low-dose cisplatin and 5-fluorouracil
Shinkawa, H.; Wada, N.; Naka, S.; Yasuhara, H.; Kuroda, T.; Nojiri, T.; Inoue, T.; Fujita, T.; Furuya, Y.; Okazaki, K.; Nagao, T.; Nagao, K.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 27(6): 909-913
2000
ISSN/ISBN: 0385-0684 PMID: 10897220 Document Number: 523152
A 68-year-old man who had Borrmann type 4 gastric cancer with multiple liver metastases was admitted to our hospital on October 20, 1998. He was considered nonresectable and placed on neoadjuvant chemotherapy consisting of low-dose CDDP and 5-FU. After 9 weeks of administration, the liver metastases had disappeared on abdominal computed tomography, but the primary lesion had progressed. On May 12, 1999, a total gastrectomy with a partial resection of the transverse colon and resectional biopsy of a white nodule of the liver were performed. This was a non-curative operation because of the peritoneal dissemination. A histopathological examination of the liver nodule revealed that the cancer cells had disappeared. The patient had an uneventful postoperative course and 4 weeks of chemotherapy were added. He remains alive with no symptoms or re-growth of the liver metastatic tumor 4 months after the surgery.