Synthesis and cloning of a human beta-casomorphin-5 gene
Hoffmann, S.; Günther, E.; Kunze, G.; Bärwolff, D.; Teppke, M.; Barth, A.
Nucleic Acids Symposium Series 18: 229-232
1987
ISSN/ISBN: 0261-3166 PMID: 3697133 Document Number: 295165
As so far a singularity among opioid peptides, bovine beta-casomorphin-5 has been shown to display pronounced cardiatic activities. The gene sequence of a human beta-casomorphin-5, including plasmid insertion and fusion protein expression and cleavage instrumentary, has been synthesized by a manual phosphoramidite procedure and cloned in a bacterial system.
Document emailed within 1 workday
Related Documents
Babkina, I.N.; Seregin, S.V.; Daniliuk, N.K.; Siniakov, A.N.; Gladkova, S.E.; Pozdniakov, S.G. 1995: Chemico-enzymatic synthesis, cloning and expression of a gene for an analog of human anaphylatoxin C5a Bioorganicheskaia Khimiia 21(5): 359-364Rosenthal, A.; Ulrich, R.; Billwitz, H.; Frank, R.; Blöcker, H. 1987: Chemical-enzymatic synthesis, cloning and expression of a synthetic gene coding for an env protein fragment of the human T-cell leukemia virus type 1 Nucleic Acids Symposium Series 18: 233-236
Kuroki, M.; Yamada, H.; Shibaguchi, H.; Hachimine, K.; Hirose, Y.; Kinugasa, T.; Ishida, I.; Kuroki, M. 2005: Preparation of human IgG and IgM monoclonal antibodies for MK-1/Ep-CAM by using human immunoglobulin gene-transferred mouse and gene cloning of their variable regions Anticancer Research 25(6a): 3733-3739
MacInnes, M.A.; Mudgett, J.S. 1990: Cloning of the functional human excision repair gene ERCC-5: potential gene regulatory features conserved with other human repair genes Progress in Clinical and Biological Research 340a: 265-274
Limborskaia, S.A.; Bukhman, V.L.; Prosniak, M.I.; Fedorov, A.N.; Slominskiĭ, P.A. 1987: Molecular causes of thalassemia. IV. Cloning of the beta-globin gene in a patient with beta-thalassemia from Azerbaijan and determination of the point mutation in a minor intron Genetika 23(2): 228-238
López-Armada, M.J.; Gómez-Guerrero, C.; Egido, J. 1996: Receptors for immune complexes activate gene expression and synthesis of matrix proteins in cultured rat and human mesangial cells: role of TGF-beta Journal of Immunology 157(5): 2136-2142
Ray, M.K.; Magdaleno, S.; O'Malley, B.W.; DeMayo, F.J. 1993: Cloning and characterization of the mouse Clara cell specific 10 kDa protein gene: comparison of the 5'-flanking region with the human rat and rabbit gene Biochemical and Biophysical Research Communications 197(1): 163-171
Becker, A.; Hempel, G.; Grecksch, G.; Matthies, H. 1990: Effects of beta-casomorphin derivatives on gastrointestinal transit in mice Biomedica Biochimica Acta 49(11): 1203-1207
Dubynin, V.A.; Maklakova, A.S.; Nezavibat'ko, V.N.; Alfeeva, L.A.; Kamenskiĭ, A.A.; Ashmarin, I.P. 1992: Effects of systemically-administered beta-casomorphin-7 on nociception in rats Biulleten' Eksperimental'noi Biologii i Meditsiny 114(9): 284-286
Kim, I.Y.; Ahn, H.J.; Zelner, D.J.; Shaw, J.W.; Sensibar, J.A.; Kim, J.H.; Kato, M.; Lee, C. 1996: Genetic change in transforming growth factor beta (TGF-beta) receptor type i gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells Cancer Research 56(1): 44-48
Bao, Y.; Fan, X.; Shu, X.; Liu, B.; Wu, J.; Lei, B. 1999: Sub-cloning and preliminary sequence analysis of the gene encoding of a cefoperazone hydrolyzing beta-lactamase isolated from Escherichia coli Hua Xi Yi Ke da Xue Xue Bao 30(3): 245-248
Griffiths, O.; McSherry, B. 2001: Human cloning offences: the gene Technology Act 2000 (Cth) Journal of Law and Medicine 9(1): 14-17
Li, X.; Liu, B.; Ji, C.N.; Kang, Y.; Mao, Y. 2006: Cloning and expression of ARMC3_v2, a novel splicing variant of the human ARMC3 gene Genetika 42(7): 999-1003
Iankevits, E.K.; Makarenkova, G.I.; Romanchikova, N.V.; Muĭzhnieks, I.O.; Tsimanis, A.I.; Gren, E.I. 1989: Cloning and nucleotide sequence of the 5'-flanking area of the human interleukin-2 gene Bioorganicheskaia Khimiia 15(10): 1362-1365
Broude, N.E.; Monastyrskaia, G.S.; Petrukhin, K.E.; Grishin, A.V.; Kiiatkin, N.I. 1987: Primary structure of the beta-subunit of Na+,K+-ATPase from the swine kidney. II. Reverse transcription, cloning of mRNA, complete nucleotide sequence corresponding to the structural region of the gene Bioorganicheskaia Khimiia 13(1): 14-19
Mertvetsov, N.P.; Golovin, S.Ia.; Zelenin, S.M.; Morozova, T.V.; Karginov, V.A. 1987: Synthesis, cloning and determination of the primary structure of DNA complementary to mRNA of prolactin from the human pituitary gland Bioorganicheskaia Khimiia 13(12): 1687-1690
Choudhury, B.K.; Setoyama, C.; Shimada, K. 1990: Molecular cloning and sequence analysis of the human cytosolic aspartate aminotransferase gene Biochemistry International 22(3): 583-591
Li, J.-W.; Liu, Y.; Li, K.; Song, D.; Ye, Q.-P. 2010: Cloning of a fusion gene containing hGM-CSF gene and gene encoding L protein of HBV and expression in Pichia Pastoris Hepato-Gastroenterology 57(99-100): 578-582
Roth, E.F.; Shear, H.L.; Costantini, F.; Tanowitz, H.B.; Nagel, R.L. 1988: Malaria in beta-thalassemic mice and the effects of the transgenic human beta-globin gene and splenectomy Journal of Laboratory and Clinical Medicine 111(1): 35-41
Zhang, J.; Dai, J.; Zhao, E.; Lin, Y.; Zeng, L.; Chen, J.; Zheng, H.; Wang, Y.; Li, X.; Ying, K.; Xie, Y.; Mao, Y. 2004: cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type VI Acta Biochimica Polonica 51(4): 1051-1058