Clinical studies on cefuzonam in obstetric and gynecological infections
Iwase, H.; Uno, M.; Tsujii, T.; Ikeshita, H.; Hogaki, M.; Arai, K.
Japanese Journal of Antibiotics 40(5): 1037-1040
1987
ISSN/ISBN: 0368-2781 PMID: 3669282 Document Number: 293343
Seventeen patients with gynecological infections (5 cases each of Bartholin's abscess and adnexitis, 4 cases of endometritis and 1 case each of bartholinitis, pyosalpinx and vulvar abscess) were treated with cefuzonam (CZON, L-105) administered by intravenous drip infusion, 1-2 g twice daily, for 4 to 12 days (6 g to 23 g in total). The clinical effectiveness reached 94.1%, including 1 excellent case, 15 cases good, and a poor case. Bacteria were detected in 9 cases, and with CZON treatment, bacterial eradications were obtained in 6 case, but, in 3 cases, bacterial replacements were observed. No abnormal laboratory findings were noted. From the above results, CZON seemed to be a highly effective and useful agent for gynecological infections.