Clinical use of piperacillin on obstetrical and gynecological infections (Second report)
Tateno, M.; Funasaka, M.; Minami, M.; Matsui, K.
Japanese Journal of Antibiotics 35(10): 2330-2336
1982
ISSN/ISBN: 0368-2781 PMID: 6223150 Document Number: 187648
We administered piperacillin (PIPC) to patients with obstetrical and gynecological infectious diseases and obtained the following results. 1. Sixteen patients were administered PIPC at a dose of 4 or 9 g by dripping infusion 2 or 3 times a day for a period of 4 approximately 14 days. Eight cases had cancer as their underlying disease (including cervical cancer etc.). The clinical effect was good in 3 of these 8 patients with cancer so that the efficacy rate was 37.5%. But the other 8 cases without cancer all responded effectively, so their efficacy rate was 100%. The efficacy was good in 11 out of 16 cases so the overall efficacy rate was 68.8%. 2. No side effect was observed. 3. No adverse reaction in laboratory findings (including hematological findings, hepatic function tests, renal function tests) was observed.