Complex formation of heparin with the inhibitor of non-enzymatic fibrinolysis isolated from the spleen
Liapina, L.A.; Ammosova, I.M.
Voprosy Meditsinskoi Khimii 33(3): 88-91
1987
ISSN/ISBN: 0042-8809 PMID: 3630024 Document Number: 291793
Formation of complexes between heparin and protein inhibitor of non-enzymatic fibrinolysis, isolated from spleen tissue of healthy animals, was demonstrated by means of cross electrophoresis, UV- and IR-spectrophotometries. Suppression of the spleen inhibitor activity towards non-enzymatic fibrinolysis occurred via its complex-formation with heparin, where the inhibitor aminogroups reacted with sulfo- or carboxyl groups of heparin.
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