Low-dose calcium-heparin prophylaxis in thoracic surgery. Bleeding, changes in coagulation and fibrinolysis
Marchetti, V.; Beati, C.; Pogliani, E.M.; Vincre, G.
Minerva Medica 74(28-29): 1745-1748
1983
ISSN/ISBN: 0026-4806 PMID: 6866306 Document Number: 197108
In a controlled, randomized study of patients undergoing thoracic surgery, calcium heparin prophylaxis is confirmed to prevent activation of the coagulation and fibrinolysis system, by determining plasmatic kallikrein, antitrombin III, and plasmin. In a further study calcium heparin, 5000 I.U. s.c. every 8 hr, is statistically proved not to increase post-operatory bleeding.
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