Pathology of canine lentiginosis profusa
Van Rensburg, I.B.; Briggs, O.M.
Journal of the South African Veterinary Association 57(3): 159-161
1986
ISSN/ISBN: 1019-9128 PMID: 3806560 Document Number: 284855
Lentiginosis profusa was diagnosed in 3 pedigree Pugs (two unrelated parents and their female offspring). Macroscopically the lentigines appeared as black macules up to 10 mm in diameter and occurred especially in the skin of the ventral parts of the body. Skin biopsies revealed localised acanthosis and hyperkeratosis with prominent rete ridges and epidermal hyperpigmentation in the absence of any other significant dermal pathology.