White lentiginosis
Grosshans, E.; Sengel, D.; Heid, E.
Annales de Dermatologie et de Venereologie 121(1): 7-10
1994
ISSN/ISBN: 0151-9638 PMID: 8092738 Document Number: 436693
A congenital guttate hypomelanosis is an unusual feature not yet mentioned in the dermatologic literature. We observed 1982 in a 28 y. female patient numerous guttate lesions, which were flat and pigmented on the light-exposed areas of her limbs, flat or papulokeratotic and depigmented on her trunk. These lesions disclosed a particular histological aspect characterized by a lentiginous hyperplasia of the epidermis, with elongated club-shaped rete ridges, and an unusual loss of pigmentation without disturbance of the keratinization. Further electronmicroscopical and immunohistochemical data were not available. The patient emphasized the congenital occurrence of these lesions, whose fixity could be assessed during a 4 year-follow up time. The unusual histological aspect allows the differentiation of these depigmented spots and other known similar conditions: macular leucoderma as sequellae of previous inflammatory diseases, hypomelanotic macules associated with genodermatoses, idiopathic guttate hypomelanoses. This seems to be a not yet described entity which we propose to denominate "white lentiginosis".