The susceptibility of a dog kidney cell-line (MDCK) to canine distemper, infectious canine hepatitis and canine herpes virus

Cornwell, H.J.; Weir, A.R.; Wright, N.G.; Thompson, H.

Research in Veterinary Science 11(6): 580-582

1970


ISSN/ISBN: 0034-5288
PMID: 5498574
Document Number: 26225
The cells supported the replication of all three viruses. They were less susceptible to canine herpes-virus than secondary dog kidney cultures but, up to the 125th sub-culture, gave larger and more clearly defined plaques under agar. High dilutions of distemper virus produced an obvious cytopathic effect in secondary cultures within 12 days but required 3-4 weeks to produce a similar effect in kidney cell monolayers.

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