A model of duplicative transposition and gene conversion for repetitive DNA families

Ohta, T.

Genetics 110(3): 513-524

1985


ISSN/ISBN: 0016-6731
PMID: 2991083
Document Number: 266963
In the model, transposition and conversion (both unbiased) are assumed to occur both within and between the genomes in a diploid cell, and any degree of linkage intensity is incorporated. The transition equations for allelic and non-allelic identity coefficients were formulated using previous results. These results are widely applicable to many repetitive sequences, from dispersed families like transposons to tightly linked multigene families. It was shown through extensive numerical studies on equilibrium properties that duplicative transposition and gene conversion have very similar effects on non-allelic identity coefficients, but that allelism and allelic identity are greatly influenced by the relative rates of occurrence of the 2 processes.

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