Interaction between the effects of centrally administered arecoline and leucocyte pyrogen on the activity of posterior hypothalamic neurons in the rabbit

Gourine, V.N.; Tsaryuk, V.V.; Fitton, A.G.

Experientia 41(11): 1427-1428

1985


ISSN/ISBN: 0014-4754
PMID: 4065298
Document Number: 259086
In experiments with urethane-anesthetized rabbits, the alteration in the activity of posterior hypothalamic neurons resulting from intracerebroventricular injection of leucocyte pyrogen was attentuated by subsequent administration of arecolin. Atropine failed to alter the neuronal response to leucocyte pyrogen but abolished the effect of arecoline. The neuronal response to arecoline was reversed in the absence of leucocyte pyrogen.

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