Acute toxicity of uranyl nitrate and behaviour of serum lipolytic activity
Gojer, M.; Desai, D.; Sawant, V.
Indian Journal of Physiology and Pharmacology 29(2): 96-102
1985
ISSN/ISBN: 0019-5499 PMID: 4093197 Document Number: 257869
The alterations in the serum lipolytic activity of mice were studied under Uranyl nitrate (UN) intoxication. The lipemia produced as a result of UN intoxication was probed studying the alterations in the serum triacylglycerol hydrolase (EC 3.1.1.3) activity. After an intraperitoneal injection of UN (10 mg/kg and 35 mg/kg), triacylglycerol hydrolase (TAGH) activity was considerably enhanced. In the initiation phase the elevation in the activity was observed to be higher than the elevation in the maintenance phase of acute UN toxicity. The possible reasons for the elevation in the TAGH activity and its role under such intoxication is discussed.